The Fibrin Matrix Regulates Angiogenic Responses within the Hemostatic Microenvironment through Biochemical Control.

Hadjipanayi E, Kuhn PH, Moog P, Bauer AT, Kuekrek H, Mirzoyan L, Hummel A, Kirchhoff K, Salgin B, Isenburg S, Dornseifer U, Ninkovic M, Machens HG, Schilling AF.

PLoS One. 2015 Aug 28;10(8):e0135618. doi: 10.1371/journal.pone.0135618.

Regeneration through Autologous Hypoxia Preconditioned Plasma

Hadjipanayi E., Schilling A.F

Organogenesis, 2014 May 15; 10 (2)

Cell-free Carrier System for Localised Delivery of Peripheral Blood Cell - Derived Engineered Factor Signaling: Towards Development of a One-Step Device for Autologous Angiogenic Therapy.

Hadjipanayi E, Bauer AT, Moog P, Salgin B, Kuekrek H, Fersch B, Hopfner U, Meissner T, Schlüter A, Ninkovic M, Machens HG, Schilling AF.

J Control Release. 2013 Apr 18. doi:pii: S0168-3659(13)00215-0. 10.1016/j.jconrel.2013.04.008.


Hypoxia-based strategies for angiogenic induction: The dawn of a new era for ischemia therapy and tissue regeneration.

Hadjipanayi E, Schilling AF.

Organogenesis. 2013 Aug 8;9(4).


Secretome of peripheral blood mononuclear cells enhances wound healing.

Mildner M, Hacker S, Haider T, Gschwandtner M, Werba G, Barresi C, Zimmermann M, Golabi B, Tschachler E, Ankersmit HJ.

PLoS One. 2013;8(3):e60103. doi: 10.1371/journal.pone.0060103. Epub 2013 Mar 22.


Injectable system for spatio-temporally controlled delivery of hypoxia-induced angiogenic signalling.

Hadjipanayi E, Cheema U, Hopfner U, Bauer A, Machens HG, Schilling AF.

J Control Release. 2012 Aug 10;161(3):852-60. doi: 10.1016/j.jconrel.2012.04.048. Epub 2012 May 22.


 Engineering stable topography in dense bio-mimetic 3D collagen scaffolds.                                   

Alekseeva T, Hadjipanayi E, Abou Neel EA, Brown RA.

Eur Cell Mater. 2012 Jan 29;23:28-40.


Mechanisms of structure generation during plastic compression of nanofibrillar collagen hydrogel scaffolds: towards engineering of collagen.             

Hadjipanayi E, Ananta M, Binkowski M, Streeter I, Lu Z, Cui ZF, Brown RA, Mudera V.

J Tissue Eng Regen Med. 2011 Jul;5(7):505-19. doi: 10.1002/term.343. Epub 2010 Dec 9.



First implantable device for hypoxia-mediated angiogenic induction.

Hadjipanayi E, Cheema U, Mudera V, Deng D, Liu W, Brown RA.

J Control Release. 2011 Aug 10;153(3):217-24. doi: 10.1016/j.jconrel.2011.03.029. Epub 2011 Mar 31.


 Controlling physiological angiogenesis by hypoxia-induced signaling.

Hadjipanayi E, Brown RA, Mudera V, Deng D, Liu W, Cheema U.

J Control Release. 2010 Sep 15;146(3):309-17. doi: 10.1016/j.jconrel.2010.05.037. Epub 2010 Jun 9.


Oxygen consumption rate of cells in 3D culture: the use of experiment and simulation to measure kinetic parameters and optimise culture conditions.

Streeter I, Cheema U.

Analyst. 2011 Oct 7;136(19):4013-9. doi: 10.1039/c1an15249a. Epub 2011 Aug 1.



Oxygen diffusion through collagen scaffolds at defined densities: implications for cell survival in tissue models.

Cheema U, Rong Z, Kirresh O, Macrobert AJ, Vadgama P, Brown RA.

J Tissue Eng Regen Med. 2012 Jan;6(1):77-84. doi: 10.1002/term.402. Epub 2011 Feb 10.


Spatially defined oxygen gradients and vascular endothelial growth factor expression in an engineered 3D cell model.

Cheema U, Brown RA, Alp B, MacRobert AJ.

Cell Mol Life Sci. 2008 Jan;65(1):177-86.







Feb. 2017 B. Braun Melsungen AG develops EmaCure technology for clinical application


Sept. 2016 EmaCure presented at the DGPRÄC Congress in Kassel


March 2016 EmaCure wins Science4Life Award


Oct. 2015  EmaCure presented at the DGPRÄC Congress in Berlin


May 2015 EmaCure presented at the 60th PSRC Meeting in Seattle


Sept. 2014  EmaCure presented at the DGPRÄC / VDÄPC /ÖGPÄRC Congress in Munich


May 2014  EmaCure presented at the 3rd EURAPS Research Counsil Meeting in Ischia, winning award for best scientific work


March 2014  EmaCure is awarded the TUM IdeAward 2014 for best scientific  idea with market potential


Nov. 2013 Prof.A.F.Schilling to present EmaCure at TUM-IAS, Scientists meet Scientists (20.11.13 at 13.15pm)


Oct. 2013 EmaCure presented at the 1st Wund-D.A.CH 3-country Congress in Friedrichshafen, winning the Prize for best scientific work (awarded to Mr P.Moog).


Aug. 2013 Publication of international patent application on a device for preparing and delivering the EmaCure therapy.


May 2013 Prof. A.F.Schilling and Dr E.Hadjipanayi are awarded the Innovation Prize for their work on the EmaCure therapy, at the German Symposium for Biotechnology (Deutsche Biotechnologietage) in Stuttgart


May 2013 EmaCure presented at the International Investigative Dermatology (IID) Congress 2013 in Edinburgh


April 2013  ESDR (European Society for Dermatological Research) Grant awarded to Mrs. A.T.Bauer for her participation in the IID (International Investigative Dermatology) Congress 2013 in Edinburgh.


March 2013 EmaCure presented at the 17th World Congress of the International Confederation for  Plastic, Reconstructive and Aesthetic Surgery (IPRAS) in Santiago


Feb.2013 International patent  (PCT) application filed on a device for preparing and delivering the EmaCure therapy


Nov. 2012 Scientists working on the EmaCure therapy receive Best Paper Award at the IPRAS-TA/10th IQUAM Congress and Consensus Conference in Athens


Sept. 2012 EmaCure presented at the 3rd World Congress of Tissue Engineering and Regenerative Medicine (TERMIS) in Vienna


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